Author: Michael R. Rose
Date Released: 1994
Page Count: 240
Isbn10 Code: 0195061330
Isbn13 Code: 9780195061338
Review "One beauty of the evolutionary theory of aging is its testability; it stands or falls on the pattern of age-specificity of genetic effects on survival and fertility, and these are open to empirical investigation. Rose himself is a leader in this field, his work on genetics of aging in Drosophilia having become a classic demonstration both of age-specific gene effects on survival and fertility and of genes with opposing effects on fitness at different ages. He produces an excellent review of the current state of knowledge on this point, not only for the classic animal models for work on aging, 'the' nematode, fruit fly, and mouse, but also for lesser-known breeds including plants." --Science "This theory and its more elaborate mathematical workings are dealt with by Michael Rose . . . . the experimental and comparative evidence in support of the theory are critically evaluated, with the not surprising conclusion that the evolutionary perspective is a powerful paradigm with which to understand the facts of aging. This review is more than competent and fills a long empty space on the evolutionary biological bookshelf." --Times Higher Education Supplement "A welcome addition to the bookshelf . . . . forcefully champions the relevance of evolutionary theory to all aspects of research on this subject." --Nature "If you are a researcher in aging, then you will want to have Michael Rose's book for its thought-provoking and encompassing synthesis of the theories of aging from the viewpoint of an evolutionary biologist. . . .a stimulating evaluation of field observations of aging, experimental tests of aging theories, genetics of aging, and comparative studies of aging. . . .Useful and well worth its price. Certainly, there is nothing else available that so adequately brings together the evolutionary theories of aging and so competently evaluates them." --BioScience "An important book. . . .A serious and sustained attempt to change the basis, content, and direction of a whole discipline. . . .It is clearly and concisely written by one who has achieved eminence both as a theoretician and as an experimenter. . . .From now on gerontological research will be 'after Rose'." --Evolution --This text refers to the edition. About the Author Michael R. Rose is at University of California, Irvine. --This text refers to the edition.
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